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Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation - ScienceDirect
Frontiers | Parkin Levels Decrease in Fibroblasts With Progranulin (PGRN) Pathogenic Variants and in a Cellular Model of PGRN Deficiency | Molecular Neuroscience
Missense Mutations in the Progranulin Gene Linked to Frontotemporal Lobar Degeneration with Ubiquitin-immunoreactive Inclusions Reduce Progranulin Production and Secretion* - Journal of Biological Chemistry
Frontiers | Multiple Molecular Pathways Are Influenced by Progranulin in a Neuronal Cell Model–A Parallel Omics Approach | Neuroscience
PGRN/GRN improves neuronal survival. (A) Effect of GRN E on survival of... | Download Scientific Diagram
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Missense mutations in progranulin gene associated with frontotemporal lobar degeneration: study of pathogenetic features. - Abstract - Europe PMC
Progranulin as a therapeutic target in neurodegenerative diseases - ScienceDirect
Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration | Molecular Neurodegeneration | Full Text
Progranulin Facilitates Conversion and Function of Regulatory T Cells under Inflammatory Conditions
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Secreted Progranulin Is a Homodimer and Is Not a Component of High Density Lipoproteins (HDL)* - Journal of Biological Chemistry
Another piece in the progranulin puzzle: special binding between progranulin and prosaposin creates additional lysosomal access - Van Damme - 2017 - Journal of Neurochemistry - Wiley Online Library
Progranulin in Sexual Differentiation of the Developing Brain | SpringerLink
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Missense Mutations in the Progranulin Gene Linked to Frontotemporal Lobar Degeneration with Ubiquitin-immunoreactive Inclusions Reduce Progranulin Production and Secretion* - Journal of Biological Chemistry
Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease - eBioMedicine
PGRN missense-mutations are impaired in secretion. A , schematic... | Download Scientific Diagram
Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations | eNeuro